Original DVD remote control for the Lexus RX-450 with the model year 2010-2013.  If you have lost your DVD remote control,  don't return your leased vehicle until you have replaced it.    Guaranteed to work on your Lexus RX450  with the model years 2010-2013  without any programming. This model DVD unit was made specifically for Lexus factory installed system. If you have an aftermarket system (such as an Audiovox or Invision) then this will not work for you.   To check and see whether you have a factory installed system, compare the image of the DVD player in your car with the one in your vehicle owner's manual. If they do not match, you do not have a factory installed DVD system. 

Your DVD system must look like this for the remote to work for you: